Outcome of total knee arthroplasties after renal transplantation

The fate of total knee arthroplasty in renal graft recipients is unknown. We retrospectively reviewed the outcome of 16 total knee arthroplasties (TKAs) performed after renal transplantation in 12 renal graft recipients from February 1997 to December 2003. The patients (mean age 63) were submitted to a clinical evaluation using the Knee Society Score (KSS) and a radiological evaluation using the Knee Society Total Knee Arthroplasty Roentgenographic Evaluation. The follow-up period averaged 65 (range 25–107) months. No knee had to be revised and one patient died during the follow-up period. The mean knee score was 97.1 (range 93–100) and the mean function score was 87.7 (range 60–100). The alignments of the prosthetic components were correct for all but one patient who, however, kept a good knee score (95). No case of aseptic loosening or osteolysis was detected at last X-rays examination. We conclude that TKA is a safe and symptomatically effective treatment of knee osteonecrosis or severe osteoarthritis in renal graft recipients and should thus be proposed in this population when symptomatology becomes significant. Long-term follow-up studies are necessary to confirm this initial report.