CoxaPro
> Clinical Library > Welcome to the joint replacement clinical library > Matrix metalloproteinases in patients with osteoarthritis of the hip
Matrix metalloproteinases in patients with osteoarthritis of the hip. International Orthopaedics SICOT 24, 92–96 (2000). https://doi.org/10.1007/s002640000110
Hip
Link to article
Matrix metalloproteinases in patients with osteoarthritis of the hip
Masuhara, K., Bak Lee, S., Nakai, T. et al.Hip
In 78 patients undergoing a total hip replacement we examined the production of matrix metalloproteinases (MMP) by the fibroblasts from the connective tissue of the acetabulum; we then correlated these findings with clinical and radiological characteristics of the same patients. In 53 patients only MMP-2 was produced; in 15 cases MMP-1, -2 and -3 were present; and in 10 cases not only MMP-1, -2, -3 but also MMP-9. Significant differences among the clinical and radiological parameters were found in the 3 subsets. A positive correlation between the production of MMP-9 and a rapid destruction of the hip joint was found.
Link to article