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The Journal of Arthroplasty, ISSN: 0883-5403, Vol: 17, Issue: 7, Page: 948-950
Knee
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Acute renal failure after local gentamicin treatment in an infected total knee arthroplasty
Tom M. van Raaij; Loes E. Visser; Arnold G. Vulto; Jan A.N. VerhaarKnee
Local gentamicin treatment in revision surgery for infected hip and knee prostheses is well established. It is a safe and effective method compared with the systemic use of aminoglycosides. Although nephrotoxic side effects are uncommon, we report a case of acute renal failure after 2-stage revision treatment of an infected knee prosthesis with gentamicin-impregnated beads and block spacers. The combined use of beads and a cement block spacer, both gentamicin impregnated, may have induced this severe complication. Use of this procedure in elderly patients warrants careful follow-up of renal function. Copyright 2002, Elsevier Science (USA). All rights reserved.
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