Comparison of Clinical Outcome Between Simultaneous-Bilateral and Staged-Bilateral Total Knee Arthroplasty: A Systematic Review of Retrospective Studies

The purpose of this study is to conduct a systematic review assessing the clinical outcome associated with Simultaneous bilateral and staged bilateral total knee arthroplasty (TKA). A literature search for eligible studies was conducted. Eighteen retrospective comparative studies were included. Pooled results showed that the prevalence of mortality at 30 days postoperatively, pulmonary embolism, blood transfusion rate were significantly higher in simultaneous TKA group. A significantly lower rate of deep infection and revision were found in simultaneous TKA. No significant difference was seen in regard to neurological complications, deep-vein thrombosis, cardiac complications, superficial infection. Compared with staged bilateral TKA, simultaneous bilateral TKA is associated with higher rates of mortality, pulmonary embolism and blood transfusion, while decreasing the risk of deep infection and revision rate.