Commentary

This study from the Pulmonary Embolism Prevention (PEP) Trial Collaborative Group provides sound evidence for routinely considering postoperative low-dose aspirin therapy as a prophylaxis against both PE and DVT for patients who have had operative treatment for hip fracture, total hip arthroplasty, or total knee replacement. The conclusions of this study confirm a meta-analysis of about 8000 patients that also suggested that low-dose aspirin was an effective thromboembolic prophylactic agent.