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The relationship between reductions in knee loading and immediate pain response whilst wearing lateral wedged insoles in knee osteoarthritis Richard K. Jones Graham J. Chapman Laura Forsythe Matthew J. Parkes David T. Felson 2014 © 2014 The Authors. Journal of Orthopaedic Research Published by Wiley Periodicals, Inc. J Orthop Res 32:1147–1154, 2014. Open
Association of MMP‐1 ‐1607 1G/2G (rs1799750) polymorphism with primary knee osteoarthritis in the Greek population Panagiotis Lepetsos Andreas Pampanos Emmanouil Kanavakis Maria Tzetis Dimitrios Korres Athanasios G. Papavassiliou Nicolaos Efstathopoulos 2014 © 2014 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 32:1155–1160, 2014. Open
How does laxity after single radius total knee arthroplasty compare with the native knee? Nicola C. Hunt Kanishka M. Ghosh Alasdair P. Blain Kiron K. Athwal Steve P. Rushton Andrew A. Amis Lee M. Longstaff David J. Deehan 2014 © 2014 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 32:1208–1213, 2014. Open
A long non‐coding RNA, GAS5, plays a critical role in the regulation of miR‐21 during osteoarthritis Jinsoo Song Chihyun Ahn Churl‐Hong Chun Eun‐Jung Jin 2014 © 2014 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 32:1628–1635, 2014. Open
Malrotated tibial component increases medial collateral ligament tension in total knee arthroplasty Shinichi Kuriyama Masahiro Ishikawa Moritoshi Furu Hiromu Ito Shuichi Matsuda © 2014 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 32:1658–1666, 2014. Malrotation of the tibial component can lead to complications after total knee arthroplasty (TKA). Despite reports of internal rotation being associated with more severe pain or stiffness than external rotation, the biomechanical reasons remain largely unknown. We used a computer simulation model and evaluated traction forces in the lateral collateral ligament (LCL) and medial collateral ligament (MCL) with a malrotated tibial component during squatting. We also examined tibiofemoral and patellofemoral contact forces and stresses under similar conditions. A dynamic musculoskeletal knee model was simulated in three different constrained tibial geometries with a prototype component. The testing conditions were changed between 15° external and 15° internal rotation of the tibial component. With internal rotation of the tibial component, the MCL force increased progressively; the LCL force also increased, but only up to less than half of the MCL force values. A higher degree of constraint of the tibial component was associated with greater femoral rotational movement and higher MCL forces. The tibiofemoral and patellofemoral contact forces were not influenced by malrotation of the tibial component, but the contact stresses increased because of decreased contact area. This altered loading condition could cause patient complaints and polyethylene problems after TKA. Open
Susceptibility to large‐joint osteoarthritis (hip and knee) is associated with BAG6 rs3117582 SNP and the VNTR polymorphism in the second exon of the FAM46A gene on chromosome 6 Godfrey E. Etokebe Zdravko Jotanovic Radovan Mihelic Biserka Mulac‐Jericevic Tamara Nikolic Sanja Balen Branko Sestan Zlatko Dembic 2015 © 2014 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:56–62, 2015. Open
Metabolic profiling of synovial fluid in a unilateral ovine model of anterior cruciate ligament reconstruction of the knee suggests biomarkers for early osteoarthritis Beata Mickiewicz Bryan J. Heard Johnny K. Chau May Chung David A. Hart Nigel G. Shrive Cyril B. Frank Hans J. Vogel 2015 © 2014 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:71–77, 2015. Open
Synovial fluid replication in knee wear testing: An investigation of the fluid volume Jörn Reinders Robert Sonntag Jan Philippe Kretzer 2015 © 2014 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:92–97, 2015. Open
Intermittent PTH administration and mechanical loading are anabolic for periprosthetic cancellous bone Matthew J. Grosso Hayden‐William Courtland Xu Yang James P. Sutherland Kirsten Stoner Joseph Nguyen Anna Fahlgren F. Patrick Ross Marjolein C. H. van der Meulen Mathias P. Bostrom 2015 © 2014 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:163–173, 2015. Open
Impact of lesion location on the progression of osteoarthritis in a rat knee model Derrick M. Knapik Ryan K. Harrison Robert A. Siston Sudha Agarwal David C. Flanigan 2015 © 2014 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:237–245, 2015. Open
Articular contact kinematics of the knee before and after a cruciate retaining total knee arthroplasty Chunbao Li Ali Hosseini Tsung‐Yuan Tsai Young‐Min Kwon Guoan Li 2015 © 2014 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:???–???, 2015. Open
Oxidative stress‐induced apoptosis and matrix loss of chondrocytes is inhibited by eicosapentaenoic acid Shuhei Sakata Shinya Hayashi Takaaki Fujishiro Kohei Kawakita Noriyuki Kanzaki Shingo Hashimoto Kenjiro Iwasa Nobuaki Chinzei Shinsuke Kihara Masahiko Haneda Takeshi Ueha Takayuki Nishiyama Ryosuke Kuroda Masahiro Kurosaka 2015 © 2014 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:???–???, 2015. Open
Effects of high heel wear and increased weight on the knee during walking Matthew R Titchenal Jessica L Asay Julien Favre Thomas P Andriacchi Constance R Chu 2015 © 2014 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:???–???, 2015. Open
Effects of steroids on thrombogenic markers in patients undergoing unilateral total knee arthroplasty: A prospective, double‐blind, randomized controlled trial Alexander S. McLawhorn Jonathan Beathe Jacques YaDeau Valeria Buschiazzo P. Edward Purdue Yan Ma Thomas P. Sculco Kethy Jules‐Elysée 2015 © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:???–???, 2015. Open
Fibronectin splice variation in human knee cartilage, meniscus and synovial membrane: Observations in osteoarthritic knee Carla R. Scanzello Dessislava Z. Markova Ana Chee Yan Xiu Sherrill L. Adams Greg Anderson Miltiadis Zgonis Ling Qin Howard S. An Yejia Zhang 2015 © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:556–562, 2015. Open
Functionally deficient mesenchymal stem cells reside in the bone marrow niche with M2‐macrophages and amyloid‐β protein adjacent to loose total joint implants Bryan S. Margulies Sean D. DeBoyace Adrienne M. Parsons Connor G. Policastro Jessica S.S. Ee Timothy S. Damron 2014 © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:615–624, 2014. Open
Dance between biology, mechanics, and structure: A systems‐based approach to developing osteoarthritis prevention strategies Constance R. Chu Thomas P. Andriacchi 2015 © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:939–947, 2015. Open
Contribution of tibiofemoral joint contact to net loads at the knee in gait Jonathan P. Walter Nuray Korkmaz Benjamin J. Fregly Marcus G. Pandy 2015 © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:1054–1060, 2015. Open
Abnormal tibial position is correlated to early degenerative changes one year following ACL reconstruction Musa Zaid Drew Lansdown Favian Su Valentina Pedoia Lauren Tufts Sarah Rizzo Richard B. Souza Xiaojuan Li C. Benjamin Ma 2015 © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:1079–1086, 2015. Open
The role of complex clinical scenarios in the failure of modular components following revision total knee arthroplasty: A finite element study Noel Conlisk Colin R. Howie Pankaj Pankaj 2015 © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:1134–1141, 2015. Open
Effect of component mal‐rotation on knee loading in total knee arthroplasty using multi‐body dynamics modeling under a simulated walking gait Zhenxian Chen Ling Wang Yaxiong Liu Jiankang He Qin Lian Dichen Li Zhongmin Jin 2015 © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:1287–1296, 2015. Open
Intraoperative passive knee kinematics during total knee arthroplasty surgery Kathryn L. Young Michael J. Dunbar Glen Richardson Janie L. Astephen Wilson 2015 © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:1611–1619, 2015. Open
Metabolic analysis of knee synovial fluid as a potential diagnostic approach for osteoarthritis Beata Mickiewicz Jordan J. Kelly Taryn E. Ludwig Aalim M. Weljie J. Preston Wiley Tannin A. Schmidt Hans J. Vogel 2015 © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:1631–1638, 2015. Open
The effect of different types of insoles or shoe modifications on medial loading of the knee in persons with medial knee osteoarthritis: a randomised trial Richard K. Jones Graham J. Chapman Matthew J. Parkes Laura. Forsythe David T. Felson 2015 © 2015 The Authors. Journal of Orthopaedic Research Published by Wiley Periodicals, Inc. J Orthop Res 33:1646–1654, 2015. Open
Peri‐implant stress correlates with bone and cement morphology: Micro‐FE modeling of implanted cadaveric glenoids Hwabok Wee April D. Armstrong Wesley W. Flint Allen R. Kunselman Gregory S. Lewis 2015 © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:1671–1679, 2015. Open

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